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School of Public Health
College of Health Sciences, Makerere University

EDCTP Career Development Fellowship

Principal Investigator

Funder

This project has received funding from the EDCTP2 programme, supported by the European Union (grant number TMA2020CDF-3189) and the Fondation Botnar

Operational Time Range

-

Description

Project summary

Despite numerous effort and resources invested in insecticide treated bed nets (ITNs) and indoor residual spraying (IRS) in recent years locally and globally to prevent malaria, the disease continues to cause significant morbidity and mortality particularly in sub-Saharan Africa. The World Health Organization has recommended appropriate combinations of non-chemical and chemical methods of malaria vector control in the context of integrated vector management. However, studies that have used multiple methods for malaria prevention have majorly focused on ITNs and IRS. Therefore, integrated malaria prevention, which advocates the use of several malaria prevention methods beyond ITNs and IRS including improving housing quality, early closure of doors on houses, and environmental management in a holistic manner, is being explored.

Dr Musoke will undertake trainings in medical entomology, clinical trials, infectious disease epidemiology, and advanced qualitative research methodology. In addition, he will be involved in other activities such as conferences, workshops and seminars to present and share results to various audiences locally and internationally.

Dr Musoke will further explore integrated malaria prevention in rural communities in Uganda as an approach to complement existing malaria control strategies. The project will involve conducting a systematic review, implementation research, as well as development of a protocol for a future main randomised controlled trial (RCT) on integrated malaria prevention in Uganda. The systematic review and implementation research will provide information that will inform the future main RCT through developing the protocol as well as writing a grant application during the award. This research on integrated malaria prevention will build on previous related studies of Dr Musoke which were well received by the community and showed promise in contributing to national and global efforts in control of the disease. Dr Musoke’s ultimate goal is to become an independent investigator, with expertise in carrying out research on malaria prevention that will inform policy and practice in Uganda and other endemic countries.

Objectives / work packages

  1. To carry out a systematic review on integrated malaria prevention.
  2. To conduct implementation research on integrated malaria prevention.
  3. To develop a protocol for a randomised controlled trial on integrated malaria prevention.
  4. To ensure smooth management and coordination of the entire project.
  5. To ensure stakeholder engagement and research dissemination throughout the project.
  6. To undertake training and mentorship in malaria (and public health) research.

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